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tooluniverse-adverse-event-detection
Automated pipeline for detecting, quantifying, and contextualizing adverse drug event signals using FAERS disproportionality analysis, FDA label minin...
tooluniverse-antibody-engineering
AI-guided antibody optimization pipeline from preclinical lead to clinical candidate. Covers sequence humanization, structure modeling, affinity optim...
tooluniverse-binder-discovery
Systematic discovery of novel small molecule binders using 60+ ToolUniverse tools across druggability assessment, known ligand mining, similarity expa...
tooluniverse-chemical-compound-retrieval
Retrieve comprehensive chemical compound data with proper disambiguation and cross-database validation. IMPORTANT: Always use English compound names a...
tooluniverse-clinical-trial-design
Systematically assess clinical trial feasibility by analyzing 6 research dimensions. Produces comprehensive feasibility reports with quantitative enro...
tooluniverse-crispr-screen-analysis
Comprehensive skill for analyzing CRISPR-Cas9 genetic screens to identify essential genes, synthetic lethal interactions, and therapeutic targets thro...
tooluniverse-disease-research
Generate a comprehensive, detailed disease research report with full source citations. The report is created as a markdown file and progressively upda...
tooluniverse-drug-drug-interaction
Systematic analysis of drug-drug interactions with evidence-based risk scoring, mechanism identification, and clinical management recommendations. KEY...
tooluniverse-expression-data-retrieval
Retrieve gene expression experiments and multi-omics datasets with proper disambiguation and quality assessment. IMPORTANT: Always use English terms i...
tooluniverse-gene-enrichment
Perform comprehensive gene enrichment analysis including Gene Ontology (GO), KEGG, Reactome, WikiPathways, and MSigDB enrichment using both Over-Repre...
tooluniverse-gwas-drug-discovery
Transform genome-wide association studies (GWAS) into actionable drug targets and repurposing opportunities. This skill bridges genetic discoveries fr...
tooluniverse-gwas-finemapping
Identify and prioritize causal variants at GWAS loci using statistical fine-mapping and locus-to-gene predictions. Genome-wide association studies (GW...